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In Situ Hybridization Analysis of Tissue

Pennsylvania rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated July 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$54.95

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $54.95 for this service. Most negotiated rates run $46.77 to $63.10.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $55 · 10th to 90th $36 to $76
$50$100professional $55

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$54.95
Typical High
$63.10
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$20.42
Typical High
$22.91
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.84
Median
$33.88
Typical High
$40.74
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$66.07
Typical High
$117.49
Capital Blue Cross
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$25.70
Typical High
$44.67
Capital Blue Cross
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$40.74
Typical High
$72.44
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$8.13
Median
$38.02
Typical High
$54.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$28.84
Median
$53.70
Typical High
$102.33
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.47
Median
$19.50
Typical High
$34.67
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.62
Median
$33.88
Typical High
$66.07
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$47.86
Typical High
$93.33
Emblem Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.38
Median
$17.38
Typical High
$33.88
Emblem Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.20
Median
$30.20
Typical High
$60.26
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$69.18
Typical High
$109.65
Geisinger
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$26.30
Typical High
$40.74
Geisinger
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$42.66
Typical High
$69.18
Martin's Point
Setting
Facility
Modifier
26 · Professional part
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$54.95
Typical High
$64.57
Martin's Point
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$20.42
Typical High
$25.70
Martin's Point
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.84
Median
$33.88
Typical High
$40.74
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$64.57
Typical High
$67.61
UPMC Health Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$24.55
Typical High
$25.12
UPMC Health Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$40.74
Typical High
$42.66
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$69.18
Typical High
$117.49
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.13
Median
$27.54
Typical High
$42.66
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$24.55
Median
$44.67
Typical High
$75.86

Where Pennsylvania sits

The same service costs 3.5 times more in Minnesota than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 35th of 51

$54.95

MN $145DE $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.