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In Situ Hybridization Analysis of Tissue

Ohio rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$41.69

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $41.69 for this service. The price depends on where it is billed: about $39.81 from a physician practice, and about $50.12 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$39.81$32.36 to $66.07
FacilityA hospital or hospital-owned outpatient department$50.12$42.66 to $81.28

How much rates vary

Facilitymedian $50 · 10th to 90th $39 to $275Professionalmedian $40 · 10th to 90th $20 to $89
$20$50$100$200$500facility $50professional $40

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$524.81
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$31.62
Median
$56.23
Typical High
$95.50
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$50.12
Typical High
$354.81
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$19.05
Typical High
$380.19
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$31.62
Typical High
$31.62
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$20.42
Median
$32.36
Typical High
$72.44
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$11.48
Typical High
$33.88
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.42
Median
$20.42
Typical High
$60.26
Cigna
Setting
Facility
Modifier
None
Typical Low
$38.90
Median
$47.86
Typical High
$194.98
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$29.51
Median
$35.48
Typical High
$89.13
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.75
Median
$13.49
Typical High
$34.67
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$21.88
Typical High
$54.95
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$42.66
Median
$50.12
Typical High
$194.98
Medical Mutual of Ohio
Setting
Professional
Modifier
None (both parts)
Typical Low
$29.51
Median
$35.48
Typical High
$87.10
Medical Mutual of Ohio
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.75
Median
$13.49
Typical High
$32.36
Medical Mutual of Ohio
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$21.88
Typical High
$53.70
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$23.99
Median
$44.67
Typical High
$89.13
SummaCare
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$74.13
Typical High
$87.10
SummaCare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$28.84
Typical High
$32.36
SummaCare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.02
Median
$44.67
Typical High
$56.23
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$36.31
Median
$63.10
Typical High
$109.65
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.18
Median
$23.99
Typical High
$40.74
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.44
Median
$39.81
Typical High
$69.18
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$19.95
Median
$29.51
Typical High
$51.29
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$7.94
Median
$11.75
Typical High
$20.89
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$25.12
Median
$25.12
Typical High
$177.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.23
Median
$10.23
Typical High
$70.79

Where Ohio sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 50th of 51

$41.69

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.