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In Situ Hybridization Analysis of Tissue

North Carolina rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$69.18

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $69.18 for this service. The price depends on where it is billed: about $69.18 from a physician practice, and about $72.44 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$69.18$38.02 to $85.11
FacilityA hospital or hospital-owned outpatient department$72.44$53.70 to $182

How much rates vary

Facilitymedian $72 · 10th to 90th $33 to $182Professionalmedian $69 · 10th to 90th $30 to $107
$50$100$200facility $72professional $69

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$53.70
Median
$53.70
Typical High
$53.70
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$53.70
Typical High
$64.57
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$19.95
Typical High
$33.88
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$33.11
Typical High
$50.12
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
BCBS North Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$38.90
Typical High
$53.70
BCBS North Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$37.15
Typical High
$95.50
Cigna
Setting
Facility
Modifier
None
Typical Low
$32.36
Median
$87.10
Typical High
$181.97
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$34.67
Typical High
$107.15
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$12.88
Typical High
$38.90
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$19.05
Median
$21.88
Typical High
$69.18
Medcost
Setting
Facility
Modifier
None
Typical Low
$53.70
Median
$53.70
Typical High
$72.44
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$83.18
Median
$85.11
Typical High
$85.11
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$30.90
Typical High
$32.36
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$53.70
Median
$54.95
Typical High
$57.54
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$38.02
Median
$57.54
Typical High
$128.82
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.80
Median
$20.89
Typical High
$46.77
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.99
Median
$36.31
Typical High
$83.18
7 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$25.12
Median
$26.92
Typical High
$32.36
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.00
Median
$10.72
Typical High
$12.88
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$42.66
Median
$42.66
Typical High
$63.10
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$16.98
Median
$16.98
Typical High
$25.12
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$12.02
Median
$12.02
Typical High
$17.78
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$12.02
Median
$12.02
Typical High
$17.78
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$12.02
Median
$12.02
Typical High
$17.78

Where North Carolina sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 26th of 51

$69.18

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.