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In Situ Hybridization Analysis of Tissue

Missouri rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$74.13

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $74.13 for this service. The price depends on where it is billed: about $72.44 from a physician practice, and about $89.13 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$72.44$56.23 to $166
FacilityA hospital or hospital-owned outpatient department$89.13$70.79 to $158

How much rates vary

Facilitymedian $89 · 10th to 90th $55 to $295Professionalmedian $72 · 10th to 90th $32 to $437
$20$50$100$200facility $89professional $72

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$64.57
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$46.77
Median
$57.54
Typical High
$77.62
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$20.89
Typical High
$28.18
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$32.36
Median
$36.31
Typical High
$48.98
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$23.99
Median
$57.54
Typical High
$141.25
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$20.89
Typical High
$83.18
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.42
Median
$37.15
Typical High
$147.91
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$81.28
Median
$83.18
Typical High
$158.49
BCBS Kansas City
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$67.61
Typical High
$102.33
Cigna
Setting
Facility
Modifier
None
Typical Low
$38.90
Median
$89.13
Typical High
$213.80
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$33.88
Typical High
$102.33
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.22
Median
$12.59
Typical High
$40.74
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.62
Median
$21.88
Typical High
$61.66
Medica
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$134.90
Typical High
$295.12
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$436.52
Typical High
$436.52
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$158.49
Typical High
$158.49
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.90
Median
$281.84
Typical High
$281.84
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$40.74
Median
$74.13
Typical High
$173.78
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.79
Median
$27.54
Typical High
$63.10
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$25.70
Median
$46.77
Typical High
$109.65
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$26.30
Median
$28.84
Typical High
$38.90
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.47
Median
$11.48
Typical High
$15.49

Where Missouri sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 22nd of 51

$74.13

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.