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In Situ Hybridization Analysis of Tissue

Michigan rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$69.18

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $69.18 for this service. The price depends on where it is billed: about $67.61 from a physician practice, and about $74.13 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$67.61$57.54 to $97.72
FacilityA hospital or hospital-owned outpatient department$74.13$57.54 to $107

How much rates vary

Facilitymedian $74 · 10th to 90th $49 to $132Professionalmedian $68 · 10th to 90th $45 to $98
$10$20$50$100$200facility $74professional $68

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$58.88
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$19.05
Median
$23.99
Typical High
$39.81
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$7.76
Median
$9.55
Typical High
$15.85
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$35.48
Median
$38.02
Typical High
$79.43
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$57.54
Median
$64.57
Typical High
$64.57
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$23.99
Typical High
$23.99
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$32.36
Typical High
$32.36
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.48
Median
$12.88
Typical High
$12.88
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$39.81
Typical High
$39.81
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$48.98
Median
$74.13
Typical High
$125.89
BCBS Michigan
Setting
Professional
Modifier
None (both parts)
Typical Low
$93.33
Median
$97.72
Typical High
$97.72
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$28.84
Median
$35.48
Typical High
$112.20
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$120.23
Typical High
$131.83
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$19.05
Median
$22.91
Typical High
$39.81
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$7.76
Median
$9.33
Typical High
$15.85
Health Alliance Plan
Setting
Facility
Modifier
TC · Technical part
Typical Low
$38.02
Median
$51.29
Typical High
$85.11
Health Alliance Plan
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$61.66
Typical High
$81.28
Health Alliance Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$22.39
Typical High
$30.90
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$30.90
Median
$40.74
Typical High
$40.74
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.30
Median
$16.60
Typical High
$16.60
Health Alliance Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$29.51
Median
$38.02
Typical High
$51.29
Priority Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$28.84
Median
$33.88
Typical High
$89.13
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$38.02
Median
$60.26
Typical High
$123.03
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$22.39
Typical High
$46.77
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$25.12
Median
$38.90
Typical High
$77.62

Where Michigan sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 27th of 51

$69.18

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.