go back

In Situ Hybridization Analysis of Tissue

Maryland rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$58.88

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $58.88 for this service. Most negotiated rates run $38.90 to $66.07.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $59 · 10th to 90th $23 to $89
$50$100professional $59

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$54.95
Median
$60.26
Typical High
$61.66
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$20.42
Typical High
$21.88
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$40.74
Typical High
$40.74
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$22.91
Median
$56.23
Typical High
$66.07
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.50
Median
$20.89
Typical High
$22.39
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$42.66
Typical High
$42.66
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$38.90
Typical High
$125.89
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$13.80
Typical High
$43.65
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$19.50
Median
$25.70
Typical High
$83.18
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$83.18
Typical High
$104.71
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$30.20
Typical High
$36.31
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$42.66
Median
$53.70
Typical High
$69.18
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$42.66
Median
$60.26
Typical High
$147.91
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.80
Median
$21.38
Typical High
$50.12
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.18
Median
$38.02
Typical High
$95.50
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$64.57
Median
$64.57
Typical High
$104.71
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$23.44
Typical High
$37.15
Wellpoint
Setting
Professional
Modifier
TC · Technical part
Typical Low
$41.69
Median
$41.69
Typical High
$67.61
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$27.54
Median
$30.20
Typical High
$30.20
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.96
Median
$12.02
Typical High
$12.30

Where Maryland sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 41st of 51

$58.88

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.