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In Situ Hybridization Analysis of Tissue

Massachusetts rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated July 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$83.18

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $83.18 for this service. Most negotiated rates run $51.29 to $145.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $83 · 10th to 90th $47 to $178
$50$100$200professional $83

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$47.86
Typical High
$104.71
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$15.85
Typical High
$165.96
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$33.88
Typical High
$69.18
AllWays Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$93.33
Typical High
$436.52
AllWays Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.78
Median
$38.02
Typical High
$158.49
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$66.07
Typical High
$281.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$70.79
Typical High
$151.36
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.59
Median
$23.99
Typical High
$54.95
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.99
Median
$46.77
Typical High
$97.72
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$28.84
Median
$60.26
Typical High
$112.20
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$131.83
Typical High
$181.97
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.84
Median
$48.98
Typical High
$67.61
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$83.18
Typical High
$120.23
Mass General Brigham
Setting
Facility
Modifier
26 · Professional part
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$93.33
Typical High
$436.52
Mass General Brigham
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.78
Median
$38.02
Typical High
$158.49
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$66.07
Typical High
$281.84
United
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$100.00
Typical High
$194.98
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.78
Median
$38.02
Typical High
$70.79
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.88
Median
$66.07
Typical High
$120.23

Where Massachusetts sits

The same service costs 3.5 times more in Minnesota than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 13th of 51

$83.18

MN $145DE $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.