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In Situ Hybridization Analysis of Tissue

Illinois rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$58.88

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $56.23 from a physician practice, and about $178 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$56.23$32.36 to $87.10
FacilityA hospital or hospital-owned outpatient department$178$91.20 to $525

How much rates vary

Facilitymedian $178 · 10th to 90th $52 to $1,096Professionalmedian $56 · 10th to 90th $26 to $102
$20$50$100$200$500$1Kfacility $178professional $56

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$60.26
Typical High
$190.55
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$34.67
Median
$51.29
Typical High
$134.90
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$57.54
Typical High
$57.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$20.42
Typical High
$20.89
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$34.67
Median
$38.02
Typical High
$38.02
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$549.54
Typical High
$1,513.56
BCBS Illinois
Setting
Professional
Modifier
None (both parts)
Typical Low
$26.30
Median
$66.07
Typical High
$102.33
Cigna
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$95.50
Typical High
$177.83
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$46.77
Typical High
$102.33
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$16.22
Typical High
$37.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$30.90
Typical High
$66.07
Hally Health
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$97.72
Typical High
$371.54
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$37.15
Typical High
$263.03
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$42.66
Median
$58.88
Typical High
$134.90
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$12.30
Median
$26.30
Typical High
$43.65
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$46.77
Median
$75.86
Typical High
$138.04
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.98
Median
$27.54
Typical High
$50.12
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$29.51
Median
$46.77
Typical High
$87.10
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$23.44
Median
$35.48
Typical High
$95.50
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$9.33
Median
$14.13
Typical High
$38.90
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$27.54
Median
$28.84
Typical High
$28.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.22
Median
$11.75
Typical High
$11.75

Where Illinois sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 39th of 51

$58.88

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.