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In Situ Hybridization Analysis of Tissue

Illinois rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated July 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$57.54

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $57.54 for this service. Most negotiated rates run $50.12 to $75.86.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $58 · 10th to 90th $32 to $102
$50$100$200professional $58

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Aetna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$57.54
Typical High
$95.50
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$20.42
Typical High
$38.02
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$38.02
Typical High
$60.26
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.47
Median
$10.47
Typical High
$10.47
BCBS
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$66.07
Typical High
$102.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$36.31
Typical High
$109.65
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$13.18
Typical High
$40.74
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$23.44
Typical High
$69.18
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$114.82
Typical High
$501.19
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.30
Median
$41.69
Typical High
$302.00
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$40.74
Median
$66.07
Typical High
$245.47
Molina
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$27.54
Typical High
$43.65
United
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$70.79
Typical High
$125.89
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.98
Median
$26.30
Typical High
$46.77
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$29.51
Median
$46.77
Typical High
$77.62

Where Illinois sits

The same service costs 3.5 times more in Minnesota than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 30th of 51

$57.54

MN $145DE $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.