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In Situ Hybridization Analysis of Tissue

Florida rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$45.71

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $45.71 for this service. The price depends on where it is billed: about $45.71 from a physician practice, and about $48.98 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$45.71$35.48 to $64.57
FacilityA hospital or hospital-owned outpatient department$48.98$38.02 to $77.62

How much rates vary

Facilitymedian $49 · 10th to 90th $34 to $162Professionalmedian $46 · 10th to 90th $28 to $89
$50$100$200facility $49professional $46

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$48.98
Typical High
$173.78
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$38.02
Median
$48.98
Typical High
$57.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.80
Median
$17.38
Typical High
$20.42
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$24.55
Median
$31.62
Typical High
$37.15
AvMed
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$51.29
Typical High
$93.33
AvMed
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$40.74
Typical High
$64.57
Cigna
Setting
Facility
Modifier
None
Typical Low
$25.70
Median
$43.65
Typical High
$162.18
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$45.71
Typical High
$107.15
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$15.85
Typical High
$40.74
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$19.50
Median
$28.84
Typical High
$69.18
Florida Blue
Setting
Professional
Modifier
None (both parts)
Typical Low
$36.31
Median
$64.57
Typical High
$93.33
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$26.92
Median
$46.77
Typical High
$85.11
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.88
Median
$44.67
Typical High
$151.36
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.59
Median
$16.60
Typical High
$54.95
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.38
Median
$28.18
Typical High
$97.72
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$24.55
Median
$38.90
Typical High
$38.90
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.45
Median
$14.45
Typical High
$23.44
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.05
Median
$24.55
Typical High
$28.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.59
Median
$9.77
Typical High
$11.75

Where Florida sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 49th of 51

$45.71

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.