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In Situ Hybridization Analysis of Tissue

Colorado rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$91.20

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $91.20 for this service. The price depends on where it is billed: about $87.10 from a physician practice, and about $107 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$87.10$50.12 to $138
FacilityA hospital or hospital-owned outpatient department$107$57.54 to $135

How much rates vary

Facilitymedian $107 · 10th to 90th $26 to $214Professionalmedian $87 · 10th to 90th $35 to $224
$20$50$100$200facility $107professional $87

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$43.65
Median
$50.12
Typical High
$79.43
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$107.15
Median
$125.89
Typical High
$223.87
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$72.44
Median
$138.04
Typical High
$245.47
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.12
Median
$48.98
Typical High
$85.11
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$46.77
Median
$91.20
Typical High
$158.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$23.44
Median
$52.48
Typical High
$125.89
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$26.92
Median
$34.67
Typical High
$128.82
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$9.55
Median
$12.59
Typical High
$50.12
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$17.78
Median
$22.39
Typical High
$79.43
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$64.57
Typical High
$93.33
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$95.50
Typical High
$275.42
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.84
Median
$34.67
Typical High
$95.50
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$50.12
Median
$60.26
Typical High
$177.83
Select Health
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$123.03
Typical High
$138.04
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$56.23
Median
$60.26
Typical High
$165.96
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$36.31
Median
$47.86
Typical High
$151.36
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$17.38
Typical High
$54.95
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.99
Median
$30.90
Typical High
$97.72

Where Colorado sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 12th of 51

$91.20

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.