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In Situ Hybridization Analysis of Tissue

Colorado rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated July 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$50.12

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $50.12 for this service. Most negotiated rates run $48.98 to $75.86.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $50 · 10th to 90th $41 to $115
$50$100professional $50

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$50.12
Typical High
$79.43
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$18.20
Typical High
$26.30
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$26.30
Median
$32.36
Typical High
$52.48
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$72.44
Typical High
$123.03
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.12
Median
$25.12
Typical High
$42.66
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$46.77
Median
$46.77
Typical High
$81.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$38.02
Typical High
$109.65
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$9.55
Median
$15.49
Typical High
$40.74
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$17.78
Median
$26.92
Typical High
$69.18
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$93.33
Median
$93.33
Typical High
$93.33
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$33.88
Typical High
$33.88
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Select Health
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$83.18
Typical High
$165.96
Select Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$30.20
Typical High
$60.26
Select Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$52.48
Typical High
$104.71
United
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$47.86
Typical High
$147.91
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$17.38
Typical High
$52.48
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$25.12
Median
$30.90
Typical High
$95.50

Where Colorado sits

The same service costs 3.5 times more in Minnesota than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 47th of 51

$50.12

MN $145DE $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.