go back

In Situ Hybridization Analysis of Tissue

Alabama rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$58.88

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $58.88 for this service. Most negotiated rates run $47.86 to $58.88.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $59 · 10th to 90th $59 to $59Professionalmedian $48 · 10th to 90th $28 to $76
$50$100$200$500facility $59professional $48

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$66.07
Typical High
$66.07
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$26.30
Typical High
$26.30
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$39.81
Typical High
$39.81
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31 + 55 · Aftercare only + 99 · Multiple modifiers
Typical Low
$22.91
Median
$45.71
Typical High
$74.13
Cigna
Setting
Facility
Modifier
None
Typical Low
$32.36
Median
$33.88
Typical High
$125.89
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$27.54
Median
$27.54
Typical High
$72.44
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.23
Median
$10.23
Typical High
$37.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$17.38
Median
$17.38
Typical High
$44.67
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$41.69
Median
$47.86
Typical High
$75.86
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.22
Median
$18.20
Typical High
$27.54
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$25.12
Median
$30.20
Typical High
$46.77
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$7.94
Median
$7.94
Typical High
$10.72
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$25.12
Median
$33.11
Typical High
$33.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.00
Median
$13.18
Typical High
$13.18

Where Alabama sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 43rd of 51

$58.88

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.