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Gene Probe Study On A Tissue Sample

North Carolina rates for HCPCS 88368

A laboratory study on a tissue sample in which a marker is attached to a specific stretch of DNA, and the cells are then examined and counted to see whether a gene is present in extra copies or has been rearranged. The marker may glow under a special microscope or show as a color visible under an ordinary one. Findings of this kind guide treatment choices in cancers such as breast cancer; this covers the first probe used, and any further probes examined on the sample are charged in addition.

Rates data updated October 2026.

How much does Gene Probe Study On A Tissue Sample cost?

$151

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $151 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $166 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$89.13 to $229
FacilityA hospital or hospital-owned outpatient department$166$105 to $339

How much rates vary

Facilitymedian $166 · 10th to 90th $105 to $479Professionalmedian $141 · 10th to 90th $76 to $288
$100$200$500facility $166professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$229.09
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$104.71
Median
$104.71
Typical High
$269.15
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$32.36
Typical High
$75.86
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$72.44
Typical High
$165.96
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
BCBS North Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$141.25
Typical High
$147.91
BCBS North Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$144.54
Typical High
$251.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$229.09
Typical High
$478.63
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$67.61
Median
$107.15
Typical High
$251.19
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$38.02
Typical High
$114.82
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$70.79
Typical High
$158.49
Medcost
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$234.42
Typical High
$331.13
Medcost
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$162.18
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$223.87
Typical High
$288.40
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$67.61
Median
$87.10
Typical High
$91.20
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$138.04
Median
$141.25
Typical High
$199.53
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$75.86
Median
$125.89
Typical High
$269.15
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$40.74
Typical High
$102.33
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$83.18
Typical High
$181.97
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$112.20
Median
$114.82
Typical High
$144.54
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$44.67
Median
$45.71
Typical High
$57.54
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$31.62
Median
$32.36
Typical High
$40.74
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$31.62
Median
$32.36
Typical High
$40.74
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$31.62
Median
$32.36
Typical High
$40.74

Where North Carolina sits

The same service costs 5.4 times more in Wisconsin than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 32nd of 51

$151

WI $316AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.