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Gene Probe Study On A Tissue Sample

California rates for HCPCS 88368

A laboratory study on a tissue sample in which a marker is attached to a specific stretch of DNA, and the cells are then examined and counted to see whether a gene is present in extra copies or has been rearranged. The marker may glow under a special microscope or show as a color visible under an ordinary one. Findings of this kind guide treatment choices in cancers such as breast cancer; this covers the first probe used, and any further probes examined on the sample are charged in addition.

Rates data updated October 2026.

How much does Gene Probe Study On A Tissue Sample cost?

$245

Typical negotiated rate. In California, October 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $240 from a physician practice, and about $282 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 11 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$240$145 to $851
FacilityA hospital or hospital-owned outpatient department$282$138 to $891

How much rates vary

Facilitymedian $282 · 10th to 90th $91 to $1,230Professionalmedian $240 · 10th to 90th $89 to $1,259
$50$100$200$500$1K$2Kfacility $282professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$218.78
Typical High
$218.78
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$162.18
Median
$416.87
Typical High
$977.24
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$194.98
Median
$218.78
Typical High
$269.15
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$52.48
Median
$56.23
Typical High
$66.07
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$162.18
Typical High
$208.93
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$25.12
Median
$1,445.44
Typical High
$1,479.11
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$89.13
Median
$263.03
Typical High
$691.83
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$85.11
Typical High
$208.93
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$64.57
Median
$169.82
Typical High
$478.63
Blue Shield
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$831.76
Typical High
$1,380.38
Blue Shield
Setting
Professional
Modifier
None (both parts)
Typical Low
$144.54
Median
$204.17
Typical High
$549.54
Blue Shield
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$57.54
Typical High
$154.88
Blue Shield
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$147.91
Typical High
$389.05
Central California Alliance for Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$158.49
Median
$158.49
Typical High
$218.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$186.21
Typical High
$338.84
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$57.54
Median
$91.20
Typical High
$346.74
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$34.67
Typical High
$114.82
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$60.26
Typical High
$257.04
Contra Costa Health
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$213.80
Typical High
$263.03
Contra Costa Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$51.29
Typical High
$63.10
Contra Costa Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$15.14
Median
$162.18
Typical High
$199.53
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$186.21
Typical High
$380.19
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$61.66
Typical High
$131.83
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$114.82
Median
$181.97
Typical High
$416.87
Lucent Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,122.02
Median
$1,258.93
Typical High
$1,258.93
Lucent Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$389.05
Median
$389.05
Typical High
$416.87
Lucent Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$794.33
Median
$933.25
Typical High
$933.25
Providence
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$218.78
Typical High
$323.59
Providence
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$114.82
Typical High
$426.58
Providence
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$34.67
Typical High
$120.23
Providence
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$57.54
Typical High
$288.40
Sutter Health Plus
Setting
Professional
Modifier
None (both parts)
Typical Low
$501.19
Median
$501.19
Typical High
$501.19
United
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$912.01
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$79.43
Median
$134.90
Typical High
$676.08
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.70
Median
$43.65
Typical High
$204.17
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$54.95
Median
$95.50
Typical High
$467.74

Where California sits

The same service costs 5.4 times more in Wisconsin than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

California· 6th of 51

$245

WI $316AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.