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Genetic Probe Tissue Stain (FISH), Single Probe

South Dakota rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$282

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $288 from a physician practice, and about $200 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$145 to $355
FacilityA hospital or hospital-owned outpatient department$200$170 to $380

How much rates vary

Facilitymedian $200 · 10th to 90th $158 to $380Professionalmedian $288 · 10th to 90th $110 to $380
$100$200$500$1Kfacility $200professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$128.82
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$117.49
Median
$128.82
Typical High
$165.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$380.19
Typical High
$380.19
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$229.09
Median
$380.19
Typical High
$478.63
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$53.70
Median
$89.13
Typical High
$112.20
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$177.83
Median
$295.12
Typical High
$363.08
Medica
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$199.53
Typical High
$199.53
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$144.54
Typical High
$354.81
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$36.31
Typical High
$91.20
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$107.15
Typical High
$269.15
Midlands
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$269.15
Typical High
$338.84
Sanford Health Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$69.18
Typical High
$87.10
Sanford Health Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$134.90
Median
$199.53
Typical High
$257.04
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$109.65
Typical High
$331.13
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$27.54
Typical High
$83.18
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$83.18
Typical High
$245.47
Wellmark
Setting
Professional
Modifier
None (both parts)
Typical Low
$302.00
Median
$380.19
Typical High
$380.19

Where South Dakota sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 4th of 51

$282

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.