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Genetic Probe Tissue Stain (FISH), Single Probe

South Dakota rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated July 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$229

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $229 for this service. Most negotiated rates run $148 to $339.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $229 · 10th to 90th $117 to $479
$100$200$500professional $229

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$31.62
Median
$31.62
Typical High
$31.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$147.91
Typical High
$194.98
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$204.17
Typical High
$204.17
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$70.79
Median
$371.54
Typical High
$380.19
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$89.13
Median
$89.13
Typical High
$89.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$380.19
Typical High
$478.63
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$67.61
Median
$89.13
Typical High
$112.20
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$223.87
Median
$295.12
Typical High
$363.08
Medica
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$144.54
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$36.31
Typical High
$323.59
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$107.15
Typical High
$870.96
Midlands
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$72.44
Median
$81.28
Typical High
$81.28
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$223.87
Median
$223.87
Typical High
$229.09
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$288.40
Typical High
$338.84
Sanford Health Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$57.54
Median
$74.13
Typical High
$83.18
Sanford Health Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$218.78
Typical High
$257.04
United
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$151.36
Typical High
$398.11
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$43.65
Typical High
$114.82
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$81.28
Median
$107.15
Typical High
$302.00
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$363.08
Typical High
$380.19
Wellmark
Setting
Professional
Modifier
26 · Professional part
Typical Low
$72.44
Median
$87.10
Typical High
$91.20
Wellmark
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$275.42
Typical High
$288.40

Where South Dakota sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 8th of 51

$229

AK $427FL $123

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.