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Genetic Probe Tissue Stain (FISH), Single Probe

South Carolina rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$145

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $138 from a physician practice, and about $245 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$138$95.50 to $166
FacilityA hospital or hospital-owned outpatient department$245$158 to $324

How much rates vary

Facilitymedian $245 · 10th to 90th $107 to $427Professionalmedian $138 · 10th to 90th $76 to $200
$50$100$200$500$1Kfacility $245professional $138

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$131.83
Typical High
$204.17
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$32.36
Typical High
$54.95
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$100.00
Median
$100.00
Typical High
$154.88
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$43.65
Typical High
$45.71
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$229.09
Typical High
$354.81
BCBS South Carolina
Setting
Facility
Modifier
TC · Technical part
Typical Low
$147.91
Median
$147.91
Typical High
$147.91
BCBS South Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$79.43
Median
$138.04
Typical High
$158.49
BCBS South Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$58.88
Typical High
$107.15
BCBS South Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.89
Median
$30.90
Typical High
$117.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$323.59
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$83.18
Typical High
$177.83
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$27.54
Typical High
$95.50
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.84
Median
$53.70
Typical High
$107.15
Medcost
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$199.53
Typical High
$467.74
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$100.00
Median
$186.21
Typical High
$218.78
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$60.26
Median
$77.62
Typical High
$83.18
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$109.65
Median
$109.65
Typical High
$223.87
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$38.02
Median
$154.88
Typical High
$199.53
United
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$870.96
Typical High
$1,122.02
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$95.50
Median
$138.04
Typical High
$295.12
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.30
Median
$44.67
Typical High
$109.65
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$85.11
Typical High
$186.21
7 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$66.07
Typical High
$69.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$26.30
Typical High
$27.54
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$50.12
Median
$93.33
Typical High
$125.89
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$20.42
Median
$38.02
Typical High
$50.12
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$14.13
Median
$26.30
Typical High
$35.48
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$14.13
Median
$26.30
Typical High
$35.48
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$14.13
Median
$26.30
Typical High
$35.48

Where South Carolina sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 43rd of 51

$145

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.