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Genetic Probe Tissue Stain (FISH), Single Probe

North Carolina rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$148

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $148 for this service. The price depends on where it is billed: about $148 from a physician practice, and about $204 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$148$100 to $209
FacilityA hospital or hospital-owned outpatient department$204$138 to $389

How much rates vary

Facilitymedian $204 · 10th to 90th $98 to $589Professionalmedian $148 · 10th to 90th $71 to $275
$100$200$500facility $204professional $148

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$138.04
Typical High
$263.03
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$138.04
Typical High
$316.23
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$33.88
Typical High
$93.33
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$97.72
Median
$102.33
Typical High
$218.78
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$56.23
Typical High
$77.62
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$457.09
Typical High
$457.09
BCBS North Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$102.33
Typical High
$141.25
BCBS North Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$114.82
Typical High
$263.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$281.84
Typical High
$588.84
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$60.26
Median
$87.10
Typical High
$263.03
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$32.36
Typical High
$107.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.84
Median
$64.57
Typical High
$186.21
Medcost
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$371.54
Medcost
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$190.55
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$158.49
Median
$177.83
Typical High
$295.12
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$60.26
Median
$77.62
Typical High
$95.50
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$112.20
Typical High
$213.80
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$83.18
Median
$104.71
Typical High
$275.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$34.67
Typical High
$91.20
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$48.98
Median
$81.28
Typical High
$213.80
7 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$79.43
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$27.54
Typical High
$32.36
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$83.18
Median
$83.18
Typical High
$204.17
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$33.11
Median
$33.11
Typical High
$81.28
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$23.44
Median
$23.44
Typical High
$57.54
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$23.44
Median
$23.44
Typical High
$57.54
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$23.44
Median
$23.44
Typical High
$57.54

Where North Carolina sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 41st of 51

$148

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.