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Genetic Probe Tissue Stain (FISH), Single Probe

Missouri rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$174

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $170 from a physician practice, and about $251 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$170$95.50 to $288
FacilityA hospital or hospital-owned outpatient department$251$178 to $437

How much rates vary

Facilitymedian $251 · 10th to 90th $138 to $794Professionalmedian $170 · 10th to 90th $85 to $1,148
$100$200$500$1Kfacility $251professional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$194.98
Typical High
$346.74
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$134.90
Median
$151.36
Typical High
$245.47
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$40.74
Typical High
$69.18
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$100.00
Median
$114.82
Typical High
$190.55
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$218.78
Median
$218.78
Typical High
$218.78
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$74.13
Median
$151.36
Typical High
$323.59
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$74.13
Typical High
$109.65
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$54.95
Median
$85.11
Typical High
$229.09
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$181.97
Typical High
$346.74
BCBS Kansas City
Setting
Professional
Modifier
None (both parts)
Typical Low
$165.96
Median
$190.55
Typical High
$275.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$288.40
Typical High
$562.34
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$77.62
Median
$85.11
Typical High
$234.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$22.91
Typical High
$75.86
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$52.48
Median
$64.57
Typical High
$158.49
Medica
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$316.23
Typical High
$794.33
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$1,148.15
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$323.59
Typical High
$323.59
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$81.28
Median
$870.96
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$562.34
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$95.50
Median
$162.18
Typical High
$398.11
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$45.71
Typical High
$95.50
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$120.23
Typical High
$302.00
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$75.86
Typical High
$102.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$30.20
Typical High
$40.74

Where Missouri sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$174

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.