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Genetic Probe Tissue Stain (FISH), Single Probe

Minnesota rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$275

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $275 for this service. The price depends on where it is billed: about $269 from a physician practice, and about $398 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$224 to $389
FacilityA hospital or hospital-owned outpatient department$398$170 to $513

How much rates vary

Facilitymedian $398 · 10th to 90th $112 to $813Professionalmedian $269 · 10th to 90th $162 to $525
$100$200$500$1Kfacility $398professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$398.11
Typical High
$812.83
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$38.02
Median
$38.02
Typical High
$38.02
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$162.18
Median
$162.18
Typical High
$204.17
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.02
Median
$38.02
Typical High
$56.23
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$112.20
Median
$123.03
Typical High
$147.91
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$112.20
Median
$295.12
Typical High
$645.65
BCBS Minnesota
Setting
Professional
Modifier
None (both parts)
Typical Low
$223.87
Median
$331.13
Typical High
$575.44
BCBS Minnesota
Setting
Professional
Modifier
26 · Professional part
Typical Low
$52.48
Median
$79.43
Typical High
$134.90
BCBS Minnesota
Setting
Professional
Modifier
TC · Technical part
Typical Low
$169.82
Median
$251.19
Typical High
$436.52
Cigna
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$616.60
Typical High
$1,778.28
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$91.20
Median
$141.25
Typical High
$416.87
Cigna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$295.12
Median
$467.74
Typical High
$1,380.38
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$234.42
Median
$257.04
Typical High
$309.03
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$54.95
Median
$60.26
Typical High
$72.44
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$177.83
Median
$194.98
Typical High
$234.42
Health Partners
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$588.84
Typical High
$1,412.54
Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$83.18
Median
$138.04
Typical High
$331.13
Health Partners
Setting
Facility
Modifier
TC · Technical part
Typical Low
$275.42
Median
$446.68
Typical High
$1,071.52
Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$229.09
Median
$229.09
Typical High
$323.59
Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$53.70
Median
$53.70
Typical High
$75.86
Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$177.83
Median
$177.83
Typical High
$251.19
Medica
Setting
Facility
Modifier
None
Typical Low
$93.33
Median
$295.12
Typical High
$562.34
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$125.89
Median
$323.59
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$87.10
Typical High
$323.59
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$107.15
Median
$239.88
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$426.58
Median
$467.74
Typical High
$602.56
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$204.17
Typical High
$489.78
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$48.98
Typical High
$120.23
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$154.88
Typical High
$363.08
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$81.28
Typical High
$81.28
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$32.36
Median
$32.36
Typical High
$32.36
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$81.28
Typical High
$97.72
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$32.36
Median
$32.36
Typical High
$38.90

Where Minnesota sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 6th of 51

$275

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.