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Genetic Probe Tissue Stain (FISH), Single Probe

Michigan rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$200

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $200 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$162 to $263
FacilityA hospital or hospital-owned outpatient department$200$166 to $269

How much rates vary

Facilitymedian $200 · 10th to 90th $132 to $417Professionalmedian $200 · 10th to 90th $98 to $282
$10$20$50$100$200$500facility $200professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$173.78
Typical High
$213.80
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$114.82
Median
$131.83
Typical High
$251.19
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$144.54
Median
$169.82
Typical High
$213.80
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.02
Median
$40.74
Typical High
$63.10
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$102.33
Median
$128.82
Typical High
$162.18
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$229.09
Typical High
$398.11
BCBS Michigan
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$263.03
Typical High
$281.84
BCBS Michigan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$50.12
Median
$66.07
Typical High
$66.07
BCBS Michigan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$213.80
Typical High
$213.80
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$38.90
Median
$141.25
Typical High
$208.93
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$74.13
Median
$91.20
Typical High
$257.04
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$173.78
Typical High
$436.52
Health Alliance Plan
Setting
Facility
Modifier
TC · Technical part
Typical Low
$109.65
Median
$134.90
Typical High
$295.12
Health Alliance Plan
Setting
Professional
Modifier
None (both parts)
Typical Low
$162.18
Median
$186.21
Typical High
$245.47
Health Alliance Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$54.95
Typical High
$77.62
Health Alliance Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$134.90
Typical High
$162.18
Priority Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$74.13
Median
$89.13
Typical High
$234.42
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$229.09
Typical High
$478.63
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$97.72
Median
$154.88
Typical High
$275.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$51.29
Typical High
$74.13
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$60.26
Median
$104.71
Typical High
$204.17
8 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$60.26
Median
$75.86
Typical High
$125.89
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$23.99
Median
$30.20
Typical High
$50.12
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$81.28
Typical High
$85.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$32.36
Typical High
$33.88
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$60.26
Median
$72.44
Typical High
$125.89
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$23.99
Median
$28.84
Typical High
$50.12
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$102.33
Typical High
$107.15
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$40.74
Typical High
$42.66

Where Michigan sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 17th of 51

$200

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.