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Genetic Probe Tissue Stain (FISH), Single Probe

Maryland rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$155

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $155 for this service. Most negotiated rates run $48.98 to $178.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $200 · 10th to 90th $182 to $288Professionalmedian $155 · 10th to 90th $35 to $240
$10$20$50$100$200$500facility $200professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$199.53
Typical High
$288.40
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$141.25
Median
$162.18
Typical High
$288.40
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$34.67
Typical High
$77.62
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$128.82
Typical High
$223.87
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$35.48
Median
$151.36
Typical High
$177.83
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$34.67
Typical High
$47.86
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$123.03
Typical High
$138.04
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$81.28
Median
$100.00
Typical High
$338.84
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$27.54
Typical High
$74.13
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$75.86
Typical High
$263.03
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$213.80
Typical High
$288.40
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$52.48
Typical High
$70.79
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$138.04
Median
$165.96
Typical High
$223.87
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$104.71
Median
$141.25
Typical High
$338.84
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.84
Median
$38.90
Typical High
$87.10
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$69.18
Median
$109.65
Typical High
$223.87
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$154.88
Typical High
$281.84
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.02
Median
$38.02
Typical High
$64.57
Wellpoint
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$117.49
Typical High
$218.78
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$70.79
Median
$81.28
Typical High
$81.28
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.18
Median
$32.36
Typical High
$32.36

Where Maryland sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 36th of 51

$155

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.