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Genetic Probe Tissue Stain (FISH), Single Probe

Massachusetts rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated July 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$209

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $209 for this service. Most negotiated rates run $166 to $380.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $209 · 10th to 90th $123 to $490
$100$200$500$1Kprofessional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$33.11
Median
$41.69
Typical High
$223.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$165.96
Typical High
$575.44
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$61.66
Typical High
$199.53
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$100.00
Typical High
$380.19
AllWays Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$42.66
Median
$100.00
Typical High
$269.15
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$213.80
Typical High
$1,148.15
AllWays Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$56.23
Typical High
$346.74
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$165.96
Typical High
$870.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$371.54
Typical High
$489.78
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$81.28
Typical High
$109.65
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$169.82
Median
$288.40
Typical High
$389.05
Cigna
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$154.88
Typical High
$354.81
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$41.69
Typical High
$95.50
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$117.49
Typical High
$251.19
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$181.97
Typical High
$302.00
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$245.47
Typical High
$446.68
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$58.88
Typical High
$107.15
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$186.21
Typical High
$338.84
Health New England
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$91.20
Typical High
$363.08
Mass General Brigham
Setting
Facility
Modifier
26 · Professional part
Typical Low
$42.66
Median
$100.00
Typical High
$269.15
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$213.80
Typical High
$1,148.15
Mass General Brigham
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$56.23
Typical High
$346.74
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$165.96
Typical High
$870.96
United
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$229.09
Typical High
$467.74
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$72.44
Typical High
$125.89
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$165.96
Typical High
$371.54

Where Massachusetts sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 10th of 51

$209

AK $427FL $123

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.