go back

Genetic Probe Tissue Stain (FISH), Single Probe

Iowa rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$209

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $209 for this service. The price depends on where it is billed: about $204 from a physician practice, and about $355 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$204$123 to $302
FacilityA hospital or hospital-owned outpatient department$355$229 to $447

How much rates vary

Facilitymedian $355 · 10th to 90th $166 to $589Professionalmedian $204 · 10th to 90th $72 to $380
$50$100$200$500$1Kfacility $355professional $204

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$229.09
Typical High
$346.74
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$123.03
Median
$123.03
Typical High
$269.15
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$30.20
Typical High
$66.07
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$91.20
Median
$91.20
Typical High
$204.17
Cigna
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$436.52
Typical High
$436.52
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$234.42
Median
$380.19
Typical High
$478.63
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$72.44
Median
$89.13
Typical High
$123.03
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$151.36
Median
$295.12
Typical High
$363.08
Hally Health
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$208.93
Typical High
$281.84
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$70.79
Typical High
$112.20
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$144.54
Typical High
$204.17
Medica
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$354.81
Typical High
$588.84
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$158.49
Median
$275.42
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$44.67
Median
$63.10
Typical High
$323.59
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$97.72
Median
$138.04
Typical High
$870.96
Midlands
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$302.00
Typical High
$467.74
Midlands
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$436.52
Typical High
$436.52
Midlands
Setting
Professional
Modifier
None (both parts)
Typical Low
$245.47
Median
$331.13
Typical High
$331.13
Oscar Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$169.82
Typical High
$331.13
United
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$426.58
Typical High
$537.03
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$169.82
Typical High
$354.81
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$44.67
Typical High
$95.50
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$125.89
Typical High
$245.47
Wellmark
Setting
Professional
Modifier
None (both parts)
Typical Low
$354.81
Median
$380.19
Typical High
$407.38
Wellmark
Setting
Professional
Modifier
26 · Professional part
Typical Low
$85.11
Median
$91.20
Typical High
$97.72
Wellmark
Setting
Professional
Modifier
TC · Technical part
Typical Low
$269.15
Median
$288.40
Typical High
$309.03
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$60.26
Median
$60.26
Typical High
$97.72
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$24.55
Median
$24.55
Typical High
$38.90

Where Iowa sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 15th of 51

$209

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.