go back

Genetic Probe Tissue Stain (FISH), Single Probe

Colorado rates for HCPCS 88365

A laboratory technique that applies a labeled genetic probe directly to a tissue or cell sample to detect a specific gene or genetic change, often called FISH (fluorescence in situ hybridization). The probe attaches only to a matching genetic sequence, which can then be seen and counted under a specialized microscope. This test is commonly used to help diagnose or classify certain cancers and other conditions linked to a specific genetic change.

Rates data updated October 2026.

How much does Genetic Probe Tissue Stain (FISH), Single Probe cost?

$191

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $191 for this service. The price depends on where it is billed: about $191 from a physician practice, and about $339 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$191$132 to $295
FacilityA hospital or hospital-owned outpatient department$339$170 to $417

How much rates vary

Facilitymedian $339 · 10th to 90th $83 to $708Professionalmedian $191 · 10th to 90th $87 to $417
$100$200$500facility $339professional $191

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$169.82
Typical High
$309.03
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$102.33
Median
$234.42
Typical High
$478.63
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$147.91
Typical High
$251.19
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$38.90
Typical High
$69.18
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$102.33
Typical High
$190.55
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$398.11
Typical High
$707.95
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$190.55
Median
$213.80
Typical High
$645.65
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$42.66
Median
$48.98
Typical High
$147.91
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$147.91
Median
$165.96
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$165.96
Typical High
$407.38
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$69.18
Median
$89.13
Typical High
$302.00
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$28.18
Typical High
$91.20
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$67.61
Typical High
$213.80
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$169.82
Typical High
$245.47
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$251.19
Typical High
$389.05
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$58.88
Typical High
$107.15
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$138.04
Median
$194.98
Typical High
$288.40
Select Health
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$331.13
Typical High
$371.54
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$125.89
Median
$177.83
Typical High
$436.52
United
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$776.25
Typical High
$891.25
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$93.33
Median
$109.65
Typical High
$331.13
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$33.88
Typical High
$89.13
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$57.54
Median
$83.18
Typical High
$257.04
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$56.23
Median
$67.61
Typical High
$102.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$22.91
Median
$26.92
Typical High
$40.74

Where Colorado sits

The same service costs 4.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 20th of 51

$191

AK $468AL $95.50

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.