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Computer-Assisted Tissue Stain Measurement

South Carolina rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$135

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $135 for this service. The price depends on where it is billed: about $107 from a physician practice, and about $178 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$107$74.13 to $158
FacilityA hospital or hospital-owned outpatient department$178$120 to $251

How much rates vary

Facilitymedian $178 · 10th to 90th $87 to $355Professionalmedian $107 · 10th to 90th $62 to $224
$50$100$200$500$1Kfacility $178professional $107

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$87.10
Typical High
$213.80
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$87.10
Median
$87.10
Typical High
$138.04
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$33.11
Typical High
$54.95
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$53.70
Median
$53.70
Typical High
$85.11
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$43.65
Typical High
$45.71
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$81.28
Median
$177.83
Typical High
$323.59
BCBS South Carolina
Setting
Facility
Modifier
TC · Technical part
Typical Low
$107.15
Median
$107.15
Typical High
$107.15
BCBS South Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$107.15
Median
$154.88
Typical High
$162.18
BCBS South Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$63.10
Typical High
$64.57
BCBS South Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$69.18
Median
$93.33
Typical High
$95.50
Cigna
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$181.97
Typical High
$446.68
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$70.79
Typical High
$223.87
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$26.92
Typical High
$95.50
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.02
Median
$43.65
Typical High
$131.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$173.78
Typical High
$323.59
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$134.90
Median
$213.80
Typical High
$213.80
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$74.13
Median
$85.11
Typical High
$85.11
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$120.23
Median
$147.91
Typical High
$147.91
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$75.86
Typical High
$120.23
United
Setting
Facility
Modifier
None
Typical Low
$1,513.56
Median
$1,819.70
Typical High
$2,398.83
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$72.44
Median
$128.82
Typical High
$338.84
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$46.77
Typical High
$134.90
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$83.18
Typical High
$208.93
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$83.18
Median
$107.15
Typical High
$123.03
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$33.11
Median
$42.66
Typical High
$48.98
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$23.44
Median
$29.51
Typical High
$34.67
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$23.44
Median
$29.51
Typical High
$34.67
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$23.44
Median
$29.51
Typical High
$34.67

Where South Carolina sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 27th of 51

$135

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.