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Computer-Assisted Tissue Stain Measurement

Missouri rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$158

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $158 from a physician practice, and about $178 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$158$110 to $513
FacilityA hospital or hospital-owned outpatient department$178$120 to $389

How much rates vary

Facilitymedian $178 · 10th to 90th $93 to $537Professionalmedian $158 · 10th to 90th $63 to $891
$100$200$500$1K$2Kfacility $178professional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$97.72
Typical High
$138.04
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$69.18
Median
$97.72
Typical High
$144.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$36.31
Typical High
$54.95
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$51.29
Median
$63.10
Typical High
$89.13
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$39.81
Typical High
$64.57
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$60.26
Median
$158.49
Typical High
$501.19
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$67.61
Typical High
$199.53
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$93.33
Typical High
$302.00
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$234.42
Typical High
$446.68
BCBS Kansas City
Setting
Professional
Modifier
None (both parts)
Typical Low
$112.20
Median
$169.82
Typical High
$213.80
Cigna
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$162.18
Typical High
$398.11
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$53.70
Median
$64.57
Typical High
$218.78
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$23.44
Typical High
$83.18
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$37.15
Median
$40.74
Typical High
$138.04
Medica
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$245.47
Typical High
$954.99
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$125.89
Median
$891.25
Typical High
$891.25
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$338.84
Typical High
$338.84
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$79.43
Median
$549.54
Typical High
$549.54
United
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,122.02
Typical High
$1,202.26
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$69.18
Median
$128.82
Typical High
$295.12
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.70
Median
$46.77
Typical High
$109.65
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$83.18
Typical High
$186.21
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$46.77
Median
$48.98
Typical High
$66.07
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$18.62
Median
$19.95
Typical High
$26.92

Where Missouri sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 18th of 51

$158

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.