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Computer-Assisted Tissue Stain Measurement

Minnesota rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$234

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $234 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $355 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$155 to $309
FacilityA hospital or hospital-owned outpatient department$355$145 to $457

How much rates vary

Facilitymedian $355 · 10th to 90th $107 to $933Professionalmedian $195 · 10th to 90th $107 to $427
$100$200$500$1Kfacility $355professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$107.15
Median
$107.15
Typical High
$354.81
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$38.02
Median
$38.02
Typical High
$38.02
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$107.15
Median
$107.15
Typical High
$128.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.02
Median
$38.02
Typical High
$47.86
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$588.84
Typical High
$1,348.96
BCBS Minnesota
Setting
Professional
Modifier
None (both parts)
Typical Low
$158.49
Median
$275.42
Typical High
$426.58
BCBS Minnesota
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$97.72
Typical High
$154.88
BCBS Minnesota
Setting
Professional
Modifier
TC · Technical part
Typical Low
$100.00
Median
$177.83
Typical High
$269.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$407.38
Typical High
$1,174.90
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$91.20
Median
$144.54
Typical High
$416.87
Cigna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$165.96
Median
$263.03
Typical High
$758.58
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$169.82
Typical High
$229.09
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$54.95
Median
$60.26
Typical High
$81.28
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$100.00
Median
$109.65
Typical High
$147.91
Health Partners
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$389.05
Typical High
$933.25
Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$85.11
Median
$138.04
Typical High
$331.13
Health Partners
Setting
Facility
Modifier
TC · Technical part
Typical Low
$154.88
Median
$251.19
Typical High
$602.56
Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$154.88
Typical High
$218.78
Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$54.95
Median
$54.95
Typical High
$77.62
Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$100.00
Median
$100.00
Typical High
$138.04
Medica
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$234.42
Typical High
$724.44
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$125.89
Median
$295.12
Typical High
$891.25
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$120.23
Typical High
$338.84
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$190.55
Typical High
$549.54
United
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$977.24
Typical High
$1,288.25
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$77.62
Median
$269.15
Typical High
$380.19
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$97.72
Typical High
$138.04
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$50.12
Median
$169.82
Typical High
$239.88
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$53.70
Median
$53.70
Typical High
$53.70
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$21.38
Median
$21.38
Typical High
$21.38
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$53.70
Median
$53.70
Typical High
$53.70
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$21.38
Median
$21.38
Typical High
$21.38

Where Minnesota sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 4th of 51

$234

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.