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Computer-Assisted Tissue Stain Measurement

Maryland rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$105

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $105 for this service. Most negotiated rates run $77.62 to $126.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $129 · 10th to 90th $95 to $186Professionalmedian $105 · 10th to 90th $40 to $170
$50$100$200facility $129professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$128.82
Typical High
$186.21
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$95.50
Median
$104.71
Typical High
$177.83
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$35.48
Typical High
$61.66
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$69.18
Typical High
$114.82
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$39.81
Median
$104.71
Typical High
$117.49
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$35.48
Typical High
$61.66
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$64.57
Median
$69.18
Typical High
$91.20
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$53.70
Median
$77.62
Typical High
$275.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$26.92
Typical High
$95.50
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$34.67
Median
$51.29
Typical High
$181.97
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$151.36
Typical High
$190.55
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$52.48
Typical High
$63.10
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$79.43
Median
$100.00
Typical High
$125.89
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$89.13
Median
$112.20
Typical High
$275.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$39.81
Typical High
$91.20
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$57.54
Median
$72.44
Typical High
$181.97
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$125.89
Median
$125.89
Typical High
$190.55
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$43.65
Typical High
$63.10
Wellpoint
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$83.18
Typical High
$125.89
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$46.77
Median
$47.86
Typical High
$52.48
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$19.05
Median
$19.50
Typical High
$20.89

Where Maryland sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 43rd of 51

$105

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.