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Computer-Assisted Tissue Stain Measurement

Massachusetts rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated July 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$158

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $158 for this service. Most negotiated rates run $129 to $288.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $158 · 10th to 90th $93 to $398
$100$200$500$1Kprofessional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$93.33
Median
$134.90
Typical High
$549.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$45.71
Typical High
$204.17
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$56.23
Median
$89.13
Typical High
$363.08
AllWays Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$194.98
Typical High
$912.01
AllWays Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$89.13
Typical High
$363.08
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$158.49
Typical High
$562.34
BCBS
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$144.54
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$57.54
Median
$81.28
Typical High
$109.65
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$95.50
Median
$95.50
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$123.03
Typical High
$269.15
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$41.69
Typical High
$97.72
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$42.66
Median
$81.28
Typical High
$190.55
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$112.20
Typical High
$204.17
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$234.42
Typical High
$331.13
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$48.98
Median
$83.18
Typical High
$117.49
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$158.49
Typical High
$213.80
Mass General Brigham
Setting
Facility
Modifier
26 · Professional part
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$194.98
Typical High
$912.01
Mass General Brigham
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$89.13
Typical High
$363.08
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$158.49
Typical High
$562.34
United
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$190.55
Typical High
$346.74
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$72.44
Typical High
$125.89
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$123.03
Typical High
$229.09

Where Massachusetts sits

The same service costs 3.1 times more in Minnesota than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 13th of 51

$158

MN $269TX $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.