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Computer-Assisted Tissue Stain Measurement

Indiana rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$105

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $105 for this service. The price depends on where it is billed: about $91.20 from a physician practice, and about $204 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$91.20$61.66 to $132
FacilityA hospital or hospital-owned outpatient department$204$120 to $316

How much rates vary

Facilitymedian $204 · 10th to 90th $91 to $1,288Professionalmedian $91 · 10th to 90th $62 to $191
$50$100$200$500$1K$2Kfacility $204professional $91

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$107.15
Typical High
$154.88
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$56.23
Median
$95.50
Typical High
$257.04
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$83.18
Median
$91.20
Typical High
$104.71
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$34.67
Typical High
$38.02
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$51.29
Median
$56.23
Typical High
$64.57
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$72.44
Median
$72.44
Typical High
$72.44
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$19.95
Typical High
$19.95
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$1,096.48
Typical High
$1,479.11
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$61.66
Typical High
$109.65
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$22.39
Typical High
$40.74
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$39.81
Typical High
$69.18
CareSource
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$69.18
Typical High
$112.20
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$39.81
Median
$72.44
Typical High
$131.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$269.15
Typical High
$281.84
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$112.20
Typical High
$223.87
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$41.69
Typical High
$83.18
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.02
Median
$64.57
Typical High
$120.23
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$316.23
Typical High
$2,089.30
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None (both parts)
Typical Low
$117.49
Median
$158.49
Typical High
$194.98
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$57.54
Typical High
$75.86
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
TC · Technical part
Typical Low
$67.61
Median
$97.72
Typical High
$123.03
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$72.44
Median
$128.82
Typical High
$218.78
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$47.86
Typical High
$83.18
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$46.77
Median
$83.18
Typical High
$141.25
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$41.69
Median
$45.71
Typical High
$52.48
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$16.60
Median
$18.20
Typical High
$20.89

Where Indiana sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 42nd of 51

$105

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.