go back

Computer-Assisted Tissue Stain Measurement

Colorado rates for HCPCS 88361

A pathologist uses image-analysis software to measure how strongly a single special stain lit up in a tissue sample taken during a biopsy or surgery, such as a hormone-receptor or growth-protein marker used to guide cancer treatment. The computer assistance gives a more precise, repeatable score than reading the slide by eye alone. It is typically done after a tumor sample has already been stained, to help decide which therapies are likely to work.

Rates data updated October 2026.

How much does Computer-Assisted Tissue Stain Measurement cost?

$166

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $275 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$93.33 to $240
FacilityA hospital or hospital-owned outpatient department$275$107 to $776

How much rates vary

Facilitymedian $275 · 10th to 90th $48 to $1,380Professionalmedian $155 · 10th to 90th $71 to $389
$50$100$200$500$1Kfacility $275professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$89.13
Typical High
$89.13
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$89.13
Median
$89.13
Typical High
$190.55
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$30.90
Typical High
$74.13
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$56.23
Median
$57.54
Typical High
$117.49
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$776.25
Typical High
$1,380.38
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$123.03
Median
$239.88
Typical High
$426.58
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$85.11
Typical High
$147.91
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$79.43
Median
$154.88
Typical High
$275.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$100.00
Typical High
$229.09
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$56.23
Median
$70.79
Typical High
$239.88
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$27.54
Typical High
$100.00
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$42.66
Typical High
$147.91
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$125.89
Typical High
$223.87
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$169.82
Typical High
$478.63
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$50.12
Median
$58.88
Typical High
$165.96
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$95.50
Median
$112.20
Typical High
$316.23
Select Health
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$223.87
Typical High
$251.19
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$100.00
Median
$107.15
Typical High
$288.40
United
Setting
Facility
Modifier
None
Typical Low
$1,548.82
Median
$1,659.59
Typical High
$1,862.09
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$93.33
Typical High
$288.40
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.12
Median
$36.31
Typical High
$107.15
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$46.77
Median
$58.88
Typical High
$173.78
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$44.67
Median
$44.67
Typical High
$87.10
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$17.78
Median
$17.78
Typical High
$35.48

Where Colorado sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 14th of 51

$166

AK $316AL $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.