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Additional Special Marker Stain On A Tissue Sample

South Dakota rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$162

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $162 for this service. The price depends on where it is billed: about $162 from a physician practice, and about $102 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$162$138 to $186
FacilityA hospital or hospital-owned outpatient department$102$38.02 to $174

How much rates vary

Facilitymedian $102 · 10th to 90th $38 to $214Professionalmedian $162 · 10th to 90th $68 to $214
$50$100$200$500facility $102professional $162

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$38.02
Typical High
$38.02
Aetna
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Cigna
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$213.80
Typical High
$213.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$162.18
Typical High
$213.80
Medica
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$102.33
Typical High
$239.88
Medica
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$165.96
Typical High
$562.34
Midlands
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$162.18
Typical High
$162.18
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$109.65
Median
$158.49
Typical High
$186.21
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$56.23
Typical High
$181.97
Wellmark
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$213.80
Typical High
$213.80

Where South Dakota sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 6th of 51

$162

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.