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Additional Special Marker Stain On A Tissue Sample

South Carolina rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$79.43

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $79.43 for this service. The price depends on where it is billed: about $70.79 from a physician practice, and about $138 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$70.79$52.48 to $93.33
FacilityA hospital or hospital-owned outpatient department$138$85.11 to $240

How much rates vary

Facilitymedian $138 · 10th to 90th $63 to $417Professionalmedian $71 · 10th to 90th $33 to $123
$50$100$200$500facility $138professional $71

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$63.10
Typical High
$141.25
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$63.10
Typical High
$104.71
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$20.89
Typical High
$31.62
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$41.69
Median
$41.69
Typical High
$70.79
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$89.13
Typical High
$162.18
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$28.84
Typical High
$47.86
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$154.88
Typical High
$489.78
BCBS South Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$52.48
Median
$89.13
Typical High
$91.20
BCBS South Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.30
Median
$34.67
Typical High
$41.69
BCBS South Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$16.98
Median
$48.98
Typical High
$61.66
Cigna
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$169.82
Typical High
$416.87
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$31.62
Median
$33.11
Typical High
$93.33
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.72
Median
$11.22
Typical High
$31.62
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.38
Median
$21.88
Typical High
$63.10
Medcost
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$75.86
Typical High
$239.88
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$93.33
Median
$93.33
Typical High
$97.72
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$31.62
Typical High
$46.77
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$63.10
Typical High
$93.33
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$75.86
Typical High
$120.23
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$46.77
Median
$81.28
Typical High
$165.96
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$27.54
Typical High
$56.23
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$53.70
Typical High
$109.65
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$46.77
Median
$46.77
Typical High
$60.26
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$19.05
Median
$19.05
Typical High
$23.99
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$13.18
Median
$13.18
Typical High
$16.98
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$13.18
Median
$13.18
Typical High
$16.98
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$13.18
Median
$13.18
Typical High
$16.98

Where South Carolina sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 38th of 51

$79.43

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.