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Additional Special Marker Stain On A Tissue Sample

Missouri rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$97.72

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $97.72 for this service. The price depends on where it is billed: about $93.33 from a physician practice, and about $112 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$93.33$64.57 to $214
FacilityA hospital or hospital-owned outpatient department$112$85.11 to $178

How much rates vary

Facilitymedian $112 · 10th to 90th $60 to $347Professionalmedian $93 · 10th to 90th $51 to $562
$50$100$200$500facility $112professional $93

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$102.33
Typical High
$114.82
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$67.61
Median
$81.28
Typical High
$154.88
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$23.99
Typical High
$51.29
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$54.95
Typical High
$102.33
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$40.74
Median
$41.69
Typical High
$123.03
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$64.57
Median
$81.28
Typical High
$257.04
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$26.92
Typical High
$85.11
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$54.95
Typical High
$169.82
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$93.33
Typical High
$177.83
BCBS Kansas City
Setting
Professional
Modifier
None (both parts)
Typical Low
$75.86
Median
$95.50
Typical High
$151.36
Cigna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$147.91
Typical High
$263.03
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$35.48
Median
$43.65
Typical High
$125.89
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$13.80
Typical High
$42.66
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.44
Median
$30.20
Typical High
$83.18
Medica
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$100.00
Typical High
$436.52
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$69.18
Median
$562.34
Typical High
$562.34
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.39
Median
$173.78
Typical High
$173.78
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$45.71
Median
$389.05
Typical High
$389.05
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$51.29
Median
$91.20
Typical High
$218.78
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.60
Median
$29.51
Typical High
$70.79
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$34.67
Median
$63.10
Typical High
$147.91
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$34.67
Median
$38.90
Typical High
$48.98
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.13
Median
$15.49
Typical High
$19.50

Where Missouri sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 23rd of 51

$97.72

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.