go back

Additional Special Marker Stain On A Tissue Sample

Indiana rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$67.61

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $67.61 for this service. The price depends on where it is billed: about $66.07 from a physician practice, and about $112 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$32.36 to $89.13
FacilityA hospital or hospital-owned outpatient department$112$87.10 to $191

How much rates vary

Facilitymedian $112 · 10th to 90th $66 to $282Professionalmedian $66 · 10th to 90th $32 to $129
$50$100$200$500$1K$2Kfacility $112professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$72.44
Median
$97.72
Typical High
$125.89
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$21.38
Median
$28.18
Typical High
$37.15
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$51.29
Median
$77.62
Typical High
$117.49
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$66.07
Median
$67.61
Typical High
$125.89
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$21.88
Typical High
$37.15
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$44.67
Typical High
$81.28
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$43.65
Median
$89.13
Typical High
$89.13
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$12.88
Typical High
$38.90
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$31.62
Median
$61.66
Typical High
$354.81
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$31.62
Median
$31.62
Typical High
$89.13
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.47
Median
$10.47
Typical High
$25.70
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.89
Median
$20.89
Typical High
$63.10
CareSource
Setting
Facility
Modifier
None
Typical Low
$28.18
Median
$64.57
Typical High
$93.33
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$25.70
Median
$67.61
Typical High
$109.65
Cigna
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$87.10
Typical High
$190.55
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$31.62
Median
$66.07
Typical High
$141.25
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.72
Median
$20.89
Typical High
$53.70
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.89
Median
$44.67
Typical High
$91.20
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$263.03
Typical High
$2,089.30
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None (both parts)
Typical Low
$85.11
Median
$117.49
Typical High
$154.88
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$38.02
Typical High
$48.98
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$81.28
Typical High
$112.20
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$52.48
Median
$89.13
Typical High
$158.49
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.98
Median
$29.51
Typical High
$50.12
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$58.88
Typical High
$107.15
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$33.11
Median
$33.11
Typical High
$39.81
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$13.18
Median
$13.18
Typical High
$15.85

Where Indiana sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 50th of 51

$67.61

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.