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Additional Special Marker Stain On A Tissue Sample

Colorado rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$110

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $110 for this service. The price depends on where it is billed: about $102 from a physician practice, and about $148 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$102$74.13 to $174
FacilityA hospital or hospital-owned outpatient department$148$83.18 to $186

How much rates vary

Facilitymedian $148 · 10th to 90th $44 to $295Professionalmedian $102 · 10th to 90th $43 to $219
$50$100$200facility $148professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$95.50
Typical High
$169.82
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$53.70
Median
$114.82
Typical High
$245.47
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$81.28
Typical High
$131.83
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$24.55
Typical High
$38.02
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$54.95
Typical High
$95.50
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$173.78
Typical High
$309.03
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$91.20
Median
$173.78
Typical High
$309.03
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$54.95
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$120.23
Typical High
$213.80
Cigna
Setting
Facility
Modifier
None
Typical Low
$38.90
Median
$77.62
Typical High
$213.80
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.20
Median
$45.71
Typical High
$141.25
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$9.77
Median
$13.49
Typical High
$42.66
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.42
Median
$31.62
Typical High
$107.15
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$83.18
Typical High
$117.49
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$141.25
Typical High
$371.54
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$38.90
Typical High
$107.15
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$87.10
Median
$102.33
Typical High
$263.03
Select Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$181.97
Typical High
$208.93
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$83.18
Median
$87.10
Typical High
$245.47
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$40.74
Median
$56.23
Typical High
$190.55
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.18
Median
$17.78
Typical High
$58.88
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$27.54
Median
$38.90
Typical High
$128.82

Where Colorado sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 18th of 51

$110

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.