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Additional Special Marker Stain On A Tissue Sample

Alabama rates for HCPCS 88341

This covers an additional specialized stain applied to a tissue sample to detect a specific marker, beyond the first such stain already performed. These stains use targeted markers to help identify particular cell types or characteristics that support a diagnosis, often for conditions like cancer.

Rates data updated October 2026.

How much does Additional Special Marker Stain On A Tissue Sample cost?

$58.88

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $63.10 from a physician practice, and about $58.88 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$63.10$42.66 to $95.50
FacilityA hospital or hospital-owned outpatient department$58.88$58.88 to $58.88

How much rates vary

Facilitymedian $59 · 10th to 90th $59 to $59Professionalmedian $63 · 10th to 90th $31 to $95
$50$100$200facility $59professional $63

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$85.11
Median
$95.50
Typical High
$95.50
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$60.26
Median
$95.50
Typical High
$95.50
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.20
Median
$28.84
Typical High
$28.84
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$40.74
Median
$67.61
Typical High
$67.61
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31 + 55 · Aftercare only + 99 · Multiple modifiers
Typical Low
$28.84
Median
$57.54
Typical High
$87.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$56.23
Typical High
$213.80
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$30.90
Median
$30.90
Typical High
$79.43
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.47
Median
$10.47
Typical High
$38.02
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.42
Median
$20.42
Typical High
$52.48
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$53.70
Typical High
$93.33
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.98
Median
$18.62
Typical High
$29.51
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$35.48
Typical High
$64.57
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$31.62
Median
$47.86
Typical High
$47.86
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.59
Median
$19.05
Typical High
$19.05

Where Alabama sits

The same service costs 5.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$58.88

AK $347AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.