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Chromosome Sister-Strand Exchange Study

Virginia rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$174

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $229 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$107 to $204
FacilityA hospital or hospital-owned outpatient department$229$174 to $427

How much rates vary

Facilitymedian $229 · 10th to 90th $166 to $891Professionalmedian $141 · 10th to 90th $85 to $427
$100$200$500$1K$2K$5K$10Kfacility $229professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$426.58
Typical High
$891.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$162.18
Typical High
$478.63
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$724.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$85.11
Typical High
$144.54
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$630.96
Typical High
$933.25
Cigna
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$363.08
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$123.03
Typical High
$316.23
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$204.17
Typical High
$257.04
Medcost
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Medcost
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$257.04
Typical High
$371.54
Medcost
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$363.08
Sentara
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$229.09
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$229.09
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$173.78
Typical High
$257.04
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$169.82
Typical High
$346.74

Where Virginia sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 29th of 51

$174

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.