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Chromosome Sister-Strand Exchange Study

South Dakota rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$331

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $288 from a physician practice, and about $331 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$162 to $407
FacilityA hospital or hospital-owned outpatient department$331$275 to $331

How much rates vary

Facilitymedian $331 · 10th to 90th $195 to $331Professionalmedian $288 · 10th to 90th $115 to $457
$100$200$500facility $331professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$194.98
Typical High
$194.98
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$134.90
Typical High
$162.18
Cigna
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$331.13
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$239.88
Typical High
$316.23
Medica
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$162.18
Typical High
$1,230.27
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$407.38
Typical High
$478.63
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$309.03
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$331

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.