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Chromosome Sister-Strand Exchange Study

South Carolina rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$151

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $151 for this service. The price depends on where it is billed: about $138 from a physician practice, and about $398 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$138$135 to $155
FacilityA hospital or hospital-owned outpatient department$398$182 to $550

How much rates vary

Facilitymedian $398 · 10th to 90th $135 to $741Professionalmedian $138 · 10th to 90th $132 to $240
$100$200$500$1Kfacility $398professional $138

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$426.58
Typical High
$812.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$162.18
BCBS
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$426.58
Typical High
$660.69
BCBS
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$208.93
Typical High
$380.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$562.34
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$97.72
Typical High
$208.93
Medcost
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$173.78
Typical High
$331.13
United
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$416.87

Where South Carolina sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 45th of 51

$151

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.