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Chromosome Sister-Strand Exchange Study

Pennsylvania rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$162

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $162 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $389 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$132 to $166
FacilityA hospital or hospital-owned outpatient department$389$209 to $513

How much rates vary

Facilitymedian $389 · 10th to 90th $148 to $955Professionalmedian $141 · 10th to 90th $100 to $389
$100$200$500$1Kfacility $389professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$389.05
Typical High
$645.65
Aetna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$141.25
Typical High
$616.60
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$1,071.52
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$281.84
Typical High
$588.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$169.82
Typical High
$363.08
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$229.09
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$229.09
Typical High
$389.05
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$389.05
Typical High
$645.65
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$141.25
Typical High
$616.60
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$223.87
Typical High
$223.87
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$724.44
Typical High
$1,258.93
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$177.83
United
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$173.78
Typical High
$295.12

Where Pennsylvania sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 37th of 51

$162

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.