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Chromosome Sister-Strand Exchange Study

North Carolina rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$166

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $200 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$138 to $209
FacilityA hospital or hospital-owned outpatient department$200$151 to $347

How much rates vary

Facilitymedian $200 · 10th to 90th $138 to $550Professionalmedian $155 · 10th to 90th $126 to $316
$100$200$500$1Kfacility $200professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$165.96
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$138.04
Typical High
$229.09
BCBS
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$478.63
Typical High
$660.69
BCBS
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$194.98
Typical High
$389.05
Cigna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$380.19
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$123.03
Typical High
$302.00
Medcost
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Medcost
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$213.80
Typical High
$380.19
Medcost
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$316.23
Typical High
$316.23
United
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$229.09
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$128.82
Typical High
$331.13
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$831.76
Typical High
$831.76
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$1,288.25
Median
$1,288.25
Typical High
$1,288.25

Where North Carolina sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 33rd of 51

$166

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.