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Chromosome Sister-Strand Exchange Study

Massachusetts rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$251

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $251 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $398 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$170 to $355
FacilityA hospital or hospital-owned outpatient department$398$240 to $525

How much rates vary

Facilitymedian $398 · 10th to 90th $158 to $676Professionalmedian $200 · 10th to 90th $141 to $525
$100$200$500$1K$2Kfacility $398professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$389.05
Typical High
$724.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$158.49
Typical High
$660.69
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$245.47
Typical High
$562.34
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$208.93
Typical High
$1,288.25
BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$426.58
Typical High
$645.65
BCBS
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$162.18
Typical High
$162.18
Cigna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$275.42
Typical High
$416.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$204.17
Typical High
$416.87
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$1,174.90
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$251.19
Typical High
$295.12
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$239.88
Typical High
$436.52
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$245.47
Typical High
$562.34
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$208.93
Typical High
$1,288.25
United
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$173.78
Typical High
$245.47
United
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$239.88
Typical High
$446.68

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 8th of 51

$251

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.