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Chromosome Sister-Strand Exchange Study

Illinois rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$200

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$141 to $245
FacilityA hospital or hospital-owned outpatient department$288$209 to $398

How much rates vary

Facilitymedian $288 · 10th to 90th $148 to $794Professionalmedian $155 · 10th to 90th $129 to $355
$10$50$200$1Kfacility $288professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$269.15
Typical High
$478.63
Aetna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$147.91
Typical High
$354.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$407.38
Typical High
$1,778.28
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$4.47
Typical High
$131.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$389.05
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$218.78
Typical High
$316.23
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$269.15
Typical High
$398.11
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$223.87
Typical High
$223.87
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$208.93
Typical High
$346.74
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$199.53
Typical High
$281.84

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 20th of 51

$200

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.