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Chromosome Sister-Strand Exchange Study

Colorado rates for HCPCS 88245

Cells from a sample are grown in the laboratory until they divide, and their chromosomes are then examined to count how often the two matching strands of a chromosome have swapped pieces with each other. Everyone shows some of this swapping; a count well above the usual range points to an inherited condition in which cells cannot keep their DNA in good repair, such as Bloom syndrome. A finding like that leads on to targeted genetic testing and to regular checks of blood counts and general health.

Rates data updated July 2026.

How much does Chromosome Sister-Strand Exchange Study cost?

$224

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $224 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $427 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$120 to $174
FacilityA hospital or hospital-owned outpatient department$427$229 to $724

How much rates vary

Facilitymedian $427 · 10th to 90th $132 to $871Professionalmedian $132 · 10th to 90th $110 to $257
$100$200$500$1Kfacility $427professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$380.19
Typical High
$812.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$131.83
Typical High
$257.04
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$512.86
Typical High
$870.96
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$102.33
Median
$120.23
Typical High
$457.09
Cigna
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$100.00
Typical High
$331.13
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$208.93
Typical High
$309.03
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$245.47
Typical High
$354.81
Select Health
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$323.59
Typical High
$363.08
Select Health
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$173.78
Typical High
$257.04
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$190.55
Typical High
$257.04
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$123.03
Typical High
$346.74

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 13th of 51

$224

AK $389DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.