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HE4 Tumor Marker Blood Test

Virginia rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$19.50

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $15.49 from a physician practice, and about $30.90 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.49$15.49 to $19.50
FacilityA hospital or hospital-owned outpatient department$30.90$20.89 to $52.48

How much rates vary

Facilitymedian $31 · 10th to 90th $19 to $107Professionalmedian $15 · 10th to 90th $10 to $44
$10$100$1K$10Kfacility $31professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$48.98
Typical High
$125.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$16.22
Typical High
$39.81
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$83.18
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$10.23
Typical High
$15.85
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$100.00
Typical High
$134.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$21.38
Median
$52.48
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$14.45
Typical High
$23.99
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$25.12
Typical High
$30.90
Medcost
Setting
Professional
Modifier
Global
Typical Low
$29.51
Median
$29.51
Typical High
$41.69
Medcost
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$19.05
Typical High
$20.89
Medcost
Setting
Professional
Modifier
Global
Typical Low
$9.12
Median
$9.12
Typical High
$43.65
Sentara
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$29.51
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$29.51
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$8.71
Median
$20.89
Typical High
$35.48
United
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$12.59
Typical High
$22.39

Where Virginia sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 36th of 51

$19.50

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.