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HE4 Tumor Marker Blood Test

Ohio rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$19.50

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $16.60 from a physician practice, and about $28.18 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.60$11.22 to $20.42
FacilityA hospital or hospital-owned outpatient department$28.18$20.89 to $45.71

How much rates vary

Facilitymedian $28 · 10th to 90th $17 to $68Professionalmedian $17 · 10th to 90th $10 to $40
$10$20$50$100facility $28professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.60
Median
$35.48
Typical High
$67.61
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$17.38
Typical High
$67.61
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$21.88
Typical High
$38.02
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$12.59
Typical High
$26.92
CareSource
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$23.99
CareSource
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$28.18
Typical High
$28.18
Cigna
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$26.92
Typical High
$85.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$13.80
Typical High
$39.81
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$27.54
Typical High
$85.11
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$13.18
Typical High
$39.81
Molina
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$16.98
Typical High
$25.12
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$13.49
Median
$21.88
Typical High
$41.69
United
Setting
Facility
Modifier
Global
Typical Low
$10.47
Median
$20.89
Typical High
$30.90
United
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$12.30
Typical High
$29.51

Where Ohio sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 33rd of 51

$19.50

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.