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HE4 Tumor Marker Blood Test

Nebraska rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$30.20

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $30.20 for this service. The price depends on where it is billed: about $16.98 from a physician practice, and about $54.95 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.98$13.80 to $50.12
FacilityA hospital or hospital-owned outpatient department$54.95$26.30 to $170

How much rates vary

Facilitymedian $55 · 10th to 90th $14 to $251Professionalmedian $17 · 10th to 90th $13 to $138
$10$20$50$100$200facility $55professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$85.11
Typical High
$251.19
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$13.80
Typical High
$138.04
BCBS
Setting
Facility
Modifier
Global
Typical Low
$30.20
Median
$40.74
Typical High
$151.36
BCBS
Setting
Professional
Modifier
Global
Typical Low
$22.39
Median
$32.36
Typical High
$33.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$23.99
Median
$39.81
Typical High
$50.12
Medica
Setting
Facility
Modifier
Global
Typical Low
$7.41
Median
$26.30
Typical High
$100.00
Medica
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$12.59
Typical High
$22.91
Midlands
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$25.70
Typical High
$42.66
Midlands
Setting
Facility
Modifier
Global
Typical Low
$25.70
Median
$25.70
Typical High
$25.70
United
Setting
Facility
Modifier
Global
Typical Low
$8.71
Median
$18.62
Typical High
$20.89
United
Setting
Professional
Modifier
Global
Typical Low
$11.75
Median
$12.59
Typical High
$41.69

Where Nebraska sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 6th of 51

$30.20

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.