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HE4 Tumor Marker Blood Test

North Carolina rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$16.60

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $16.60 for this service. The price depends on where it is billed: about $16.60 from a physician practice, and about $19.95 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.60$16.60 to $18.62
FacilityA hospital or hospital-owned outpatient department$19.95$16.60 to $45.71

How much rates vary

Facilitymedian $20 · 10th to 90th $17 to $204Professionalmedian $17 · 10th to 90th $14 to $32
$10$20$50$100$200facility $20professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.60
Median
$18.20
Typical High
$204.17
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$16.60
Typical High
$31.62
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$14.45
Typical High
$14.45
BCBS
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$64.57
Typical High
$91.20
BCBS
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$14.45
Typical High
$19.50
Cigna
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$39.81
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$14.45
Typical High
$31.62
Medcost
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Medcost
Setting
Facility
Modifier
Global
Typical Low
$16.60
Median
$19.05
Typical High
$21.88
Medcost
Setting
Professional
Modifier
Global
Typical Low
$7.24
Median
$9.12
Typical High
$9.12
United
Setting
Facility
Modifier
Global
Typical Low
$10.72
Median
$27.54
Typical High
$36.31
United
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$14.79
Typical High
$29.51
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$97.72
Median
$97.72
Typical High
$100.00

Where North Carolina sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 46th of 51

$16.60

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.