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HE4 Tumor Marker Blood Test

Mississippi rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$23.99

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $23.99 for this service. The price depends on where it is billed: about $22.39 from a physician practice, and about $27.54 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$22.39$15.85 to $37.15
FacilityA hospital or hospital-owned outpatient department$27.54$20.89 to $37.15

How much rates vary

Facilitymedian $28 · 10th to 90th $19 to $37Professionalmedian $22 · 10th to 90th $13 to $43
$10$20$50facility $28professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$37.15
Typical High
$42.66
Aetna
Setting
Professional
Modifier
Global
Typical Low
$15.85
Median
$23.99
Typical High
$42.66
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$10.47
Median
$10.47
Typical High
$10.47
BCBS
Setting
Facility
Modifier
Global
Typical Low
$27.54
Median
$27.54
Typical High
$27.54
BCBS
Setting
Professional
Modifier
Global
Typical Low
$25.12
Median
$25.12
Typical High
$25.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$21.38
Typical High
$42.66
Cigna
Setting
Professional
Modifier
Global
Typical Low
$9.55
Median
$21.88
Typical High
$52.48
United
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$20.89
Typical High
$28.18
United
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$12.59
Typical High
$37.15

Where Mississippi sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 17th of 51

$23.99

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.