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HE4 Tumor Marker Blood Test

Michigan rates for HCPCS 86305

A blood test that measures human epididymis protein 4, a substance often raised in women with ovarian cancer. It is used together with other tests when assessing a mass on an ovary, and to follow how a known ovarian cancer responds to treatment.

Rates data updated July 2026.

How much does HE4 Tumor Marker Blood Test cost?

$19.95

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $19.95 for this service. The price depends on where it is billed: about $19.95 from a physician practice, and about $19.95 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$19.95$15.85 to $19.95
FacilityA hospital or hospital-owned outpatient department$19.95$19.95 to $24.55

How much rates vary

Facilitymedian $20 · 10th to 90th $19 to $36Professionalmedian $20 · 10th to 90th $14 to $28
$10$20$50$100facility $20professional $20

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$19.95
Typical High
$36.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$19.95
Typical High
$24.55
BCBS
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$14.45
Typical High
$14.45
BCBS
Setting
Professional
Modifier
Global
Typical Low
$13.80
Median
$14.45
Typical High
$14.45
Cigna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$20.89
Typical High
$30.20
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$20.42
Typical High
$69.18
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$25.12
Typical High
$37.15
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$22.91
Typical High
$26.92
United
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$20.89
Typical High
$20.89
United
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$16.98
Typical High
$26.92

Where Michigan sits

The same service costs 3.2 times more in Oklahoma than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 30th of 51

$19.95

OK $50.12DC $15.49

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.